Fig. 3
From: Global analysis of suppressor mutations that rescue human genetic defects
Functional connections between query and suppressor genes. A Frequency of suppression interactions connecting genes within and across indicated biological processes. Color intensity reflects the fraction of suppressor genes belonging to a particular biological process for all interactions involving query genes annotated to a given biological process. The total number of suppression interactions involving genes annotated to a particular process is indicated. B-C Fold enrichment for co-localization, co-expression, GO co-annotation, same pathway membership, and same complex membership for query-suppressor gene pairs (B) or among suppressor genes that have been described for the same query gene (C)