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Fig. 4 | Genome Medicine

Fig. 4

From: Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine

Fig. 4

Evolutionary overview of GP12 whole genome sequenced samples. a Dirichlet process clustering of GP12 single nucleotide variants (SNVs) across the cancer samples plotted as in Fig. 3a for GP5. Private mutations in samples RPelvicLNMet1 and RPelvicLNMet2 were further divided into two separate clusters. b Cladogram of the evolutionary clusters in GP12 cancer. The evolutionary tree has two non-metastatic branches, represented by clusters A and D. The lineage of branch C has undergone the most clonal expansions, putatively representing the most advanced form of the cancer. c Jawbreaker plots for GP12 samples

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Genome Medicine

ISSN: 1756-994X

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