Table 1 Patient characteristics and outcome variables of clinical cases with 261/825 invasive or 564/825 non-invasive infections. ‘Invasive infection’ was defined as at least one positive E. coli blood culture, whereas ‘non-invasive infection’ was defined as at least one E. coli-positive urine sample, with no blood culture being tested positive for E. coli. Some variables were unavailable for a subset of patients, resulting in varying denominators in the table. The numeric values ‘age’ and ‘CCI’ were compared using a Mann–Whitney U test and the factorial variables ‘sex’, ‘immunosuppression’, ‘typical UTI symptoms, ‘ICU admission’, and ‘30-day all-cause mortality’ using a Chi-squared test
Variable | All cases (n = 825) | Cases with invasive infection (n = 261) | Cases with non-invasive infection (n = 564) | p-value invasive vs. non-invasive cases |
|---|---|---|---|---|
Age [years] (median, [IQR]) | 75.3 [63.6,83.0] | 74.7 [63.7, 82.3] | 75.7 [63.4, 83.3] | 5.5 × 10−1 (ns) |
Sex = male (n (%)) | 251/825 (30.4) | 120/261 (46.0) | 131/564 (23.2) | 6.83 × 10−11 (***) |
CCI (median [IQR]) | 2 [0, 3] | 2 [0, 3] | 2 [0, 3] | 9.3 × 10−1 (ns) |
Immunosuppression = true (n (%)) | 86/811 (10.6) | 44/256 (17.2) | 42/555 (7.6) | 6.00 × 10−5 (***) |
Typical UTI symptoms | 231/778 (29.7) | 77/256 (30.1) | 154/522 (29.5) | 9.3 × 10−1 (ns) |
ICU admission | 188/821 (22.9) | 63/260 (24.2) | 125/561 (22.23) | 6.0 × 10−1 (ns) |
30-day all-cause mortality | 50/819 (6.1) | 21/258 (8.1) | 29/561 (5.2) | 1.4 × 10−1 (ns) |