The role of admixture in the rare variant contribution to inflammatory bowel disease

Table 2 Variants in Sazonovs et al. loci in African Americans, with EP-scores within pathogenic range (EP < 0.0022)

Gene	varID	rsID	Variant	EP-score	AF Case^a	AF Control^b	AF gN-AFR^c
SDF2L1	22−21643930−G−A	rs61739341	D141N	0.001	0.018	0.016	0.017
PTAFR	1−28150202−CT	rs140866472	A274T	0.002	0.012	0.011	0.013
PTAFR	1−28150940−G−A	rs116552042	L28F	0.004	0.0093	0.0061	0.007
PTGER4	5−40692215−G−A	rs138674524	R435Q	0.002	0.00057	0.0003	0.0008
SLC39A8	4−102263082−G−A	rs112519623	L449F	0.0008	0.0051	0.0015	0.003
IL10RA	11−117988495−C−G	rs4252250	L61V	0.005	0.041	0.044	0.045

ISSN: 1756-994X