Fig. 8
From: Annotation of cell types (ACT): a convenient web server for cell type annotation
Refinement and annotation of cell clusters in colon tissues. A Reclustering of cells and its UMAP projection in colon tissues. B “Ground truth” cell cluster labels derived from manual cell annotation based on the marker map. C Annotation results based on ACT. D A Sankey diagram to show the comparison of annotation results. Cell types that might be mislabeled are shown in the red box. E Epithelial cells and goblet cells correspond to the iCMS2 and iCMS3 subgroups in the original publication, respectively. CD4_Tn, Naive thymus-derived CD4-positive, alpha-beta T cell; Th17, T helper 17 cell; Treg, Regulatory T cell; CD8_Tem, Effector memory CD8-positive alpha, beta T cell; CTL, Cytotoxic T cell; NK, Natural killer cell; FO_B, Follicular B cell; Plasma, Plasma cell; mregDC, Migratory dendritic cell; Glial, Glial cell, i.e., Entericglial cell; Endo, Endothelial cell; Endo_lymphatic, Lymphatic endothelial cell; Fibro, Fibroblast; Myof, Myofibroblast cell; Goblet, Goblet cell; Epi_colon, Colon epithelial cell; Goblet_T, Malignant goblet cell; Goblet_N, Normal goblet cell; McDC, Monocyte conventional dendritic cell; pDC, Plasmacytoid dendritic cell