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Table 1 Human CLTI patient demographics (N = 10)

From: Skeletal muscle regeneration failure in ischemic-damaged limbs is associated with pro-inflammatory macrophages and premature differentiation of satellite cells

Patients (N)

Gender (M/F)

Age (mean ± SD)

BMI (mean ± SD)

Diabetes (Y/N)

HTN (Y/N)

HLD (Y/N)

CKD (Y/N)

CAD (Y/N)

ABI

Analysis

3

2/1

80 ± 8.19

30.13 ± 5.85

1/2

3/0

3/0

1/2

1/2

n/a: 3

scRNA-seq analysis

7

7/0

66 ± 10.93

23.36 ± 4.10

5/2

7/0

6/1

5/2

7/0

0.4 - 0.9: 2< 0.4: 2

NC: 2

n/a: 1

Histologic analysis

  1. ABI Ankle brachial index, BMI Body mass index, CAD Coronary artery disease, CKD Chronic kidney disease, HLD Hyperlipidemia, HTN Hypertension, n/a Not available, NC Non-compressible