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Fig. 5 | Genome Medicine

Fig. 5

From: A phenome-wide scan reveals convergence of common and rare variant associations

Fig. 5

Comparisons of gene-level signals from common and rare variants. The CORAC signature, a global statistic, and the locus-specific convergence from common and rare variants highlight the diversity of genetic architectures of human complex traits. The common and variant-based gene-level Manhattan plots illustrate the convergence level. The hollow diamonds denote the top 100 genes. Genes highly ranked in both common and rare-variant-based tests are labeled with the gene symbol and a dashed vertical line. Traits with high (a and b), low (c), and average (d) CORAC coefficients are visualized

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