Fig. 3
From: Acute ischemia induces spatially and transcriptionally distinct microglial subclusters
ICAM and IPAM exhibit distinct features. A GSVA showing biological processes differentially enriched in IPAM/ICAM. B Gene score feature plots in IPAM and ICAM using representative genes involved in glycolysis/TCA cycle/OXPHOS pathways (Additional file 2: Table S6). C Gene score feature plot for pro-inflammatory cytokines (Il1a, Il1b, Il6, Il18, Tnf, Hmox1, Ptgs2) in microglia. D Boxplots depicting macrophage/neutrophil/T cell/NK-specific chemokine expression (Additional file 2: Table S8) among four microglial subclusters using the AddModuleScore. E Gene score feature plots in IPAM and ICAM using canonical sphingolipid metabolism, UFA biosynthesis, fatty acid degradation, and fatty acid elongation marker genes (Additional file 2: Table S6)