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Fig. 7 | Genome Medicine

Fig. 7

From: GITR and TIGIT immunotherapy provokes divergent multicellular responses in the tumor microenvironment of gastrointestinal cancers

Fig. 7

A Average expression of respective genes in each sample in control or TIGIT inhibitor-treated CD8 T cells with MAST DE adjusted p. B, C Cohen’s effect size and p of t-test comparison of respective pathway activity between control and treated cells from each individual sample. D Violin plots depicting the expression of respective genes in CD8 T cells from GC-1-2 and GC-1-3 samples with Seurat Wilcoxon adjusted p. E–G Respective pathway activity in control and treated CD8 T cells with t-test p in E, F CD8 T cell subtypes and G baseline expanded CD8 TCR clonotypes per sample

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Genome Medicine

ISSN: 1756-994X

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