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Fig. 8 | Genome Medicine

Fig. 8

From: GITR and TIGIT immunotherapy provokes divergent multicellular responses in the tumor microenvironment of gastrointestinal cancers

Fig. 8

A Average expression of respective genes in each sample in control or TIGIT inhibitor-treated TFh-like cells with MAST DE adjusted p. B Cohen’s effect size and p of t-test comparison of pathway activity between control and treated TFh-like cells from each individual sample. C, D Average expression of respective genes in each sample in control or TIGIT inhibitor-treated C Treg cells and D DCs with MAST DE adjusted p. E Cohen’s effect size and p of t-test comparison of pathway activity between control and treated tumor epithelial cells from each individual sample. F Schematic representation summarizing the ex vivo effects of TIGIT antagonist in the TME

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Genome Medicine

ISSN: 1756-994X

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