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Fig. 3 | Genome Medicine

Fig. 3

From: Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature set

Fig. 3

Performance assessment. Precision-recall curves indicating the discriminatory power of various pathogenicity prediction methods and LoGoFunc on a set of variants from the test set for which predictions were available from all compared tools. a LoGoFunc’s performance on all testing variants (n. GOF = 152, n. LOF = 1340, n. neutral = 1339). b GOF (n. 136) vs. neutral (n. 411). c LOF (n. 545) vs. neutral (n. 411). d GOF (n. 136) and LOF (n. 545) combined vs. neutral (n. 411)

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Genome Medicine

ISSN: 1756-994X

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