Fig. 5From: Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature setPheWAS of predicted GOF and LOF variants. Selected examples of phenotype associations of predicted GOF and LOF variants in the BioMe BioBank. Each circle represents an association, with the circle size proportional to the natural logarithm of the odds ratios (ln(OR)). The dashed line indicates the Bonferroni-adjusted P-value thresholdBack to article page