Fig. 2
From: Prenatal BRCA1 epimutations contribute significantly to triple-negative breast cancer development
BRCA1 methylation in matched blood and tumor samples in breast cancer patients. A Molecular and histological characteristics (rows) of all samples (N = 55; columns) belonging to matched sample pairs carrying BRCA1 methylation in the blood (WBC) and/or tumor. TNBC, triple-negative breast cancer; HER2, Human epithelial-like receptor-2; ER, estrogen receptor; basal, basal-like gene expression profile; Her2, HER2-enriched gene expression profile; LumA, luminal A gene expression profile; LumB, luminal B gene expression profile; Normal, normal-like gene expression profile; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma. B Concordance of BRCA1-methylation status in WBC and tumor tissue among all patients analyzed, stratified for tumors belonging to the different breast cancer subgroups