Skip to main content
Fig. 1 | Genome Medicine

Fig. 1

From: Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in Africans without type 2 diabetes

Fig. 1

Overview of analyses performed to identify circulating cytokines and hormones causally associated with HOMA-S, HOMA-B, and/or T2D. T2D = type 2 diabetes, HOMA = homeostatic modelling assessment of insulin sensitivity and insulin secretion, GWAS = genome-wide association study, LD = linkage disequilibrium, 2SLS = two-stage least squares, IVW = inverse variance weighted, MR = Mendelian randomization, BMI = body mass index

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us