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Fig. 3 | Genome Medicine

Fig. 3

From: Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in Africans without type 2 diabetes

Fig. 3

Forest plot of univariable (blue) and multivariable (red) MR causal associations of cytokines and hormones on HOMA-S (left) and HOMA-B (right). HOMA analyses were performed in non-T2D individuals only. A Bonferroni-corrected P-value of < 0.0045 (= 0.05/11 cytokines and hormones) was considered statistically significant

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