Table 1 Characteristics of the SIREN case-control samples after QC

Baseline age (mean± SD)

59.5 ± 13.5

61.2 ± 13.7

0.0005

Sex (male/female)

924 (27.0%*)/814(23.8%)

906 (26.5%)/777 (22.7%)

0.7062

Hypertension (male/female)

No-risk

369 (10.8%)/274 (8%)

51 (1.5%)/32 (0.9%)

<0.0001

Risk

554 (16.2%)/540 (15.8%)

851 (24.9%)/742 (21.7%)

Missing

1/0

4/3

Diabetes (male/female)

No-risk

805 (23.5%)/691 (20.2%)

615 (18.0%)/458 (13.4%)

<0.0001

Risk

118 (3.4%)/123 (3.6%)

289 (8.4%)/318 (9.3%)

Missing

1/0

2/1

Dyslipidemia (male/female)

No-risk

374 (10.9%)/301 (8.8%)

252 (7.4%)/200 (5.8%)

<0.0001

Risk

549 (16.0%)/513 (15.0%)

650 (19.0%)/575 (16.8%)

Missing

1/0

4/2

Waist-to-hip ratio

0.921 ± 0.091

0.945 ± 0.078

<0.0001

Cardiac status (male/female)

No-risk

875 (25.6%)/763 (22.3%)

783 (22.9%)/668 (19.5%)

<0.0001

Risk

46 (1.3%)/51 (1.5%)

117 (3.4%)/106 (3.1%)

Missing

3/0

6/3

Ethnicity (male/female)

Akan

239/203

207/206

Yoruba

354/304

355/272

Hausa

149/135

138/126

GA/Adangbe

40/41

44/39

Ewe

39/24

34/24

Igbo

34/24

28/20

Other

69/74

95/83

Missing

0/7

5/7

Toast status (male/female)

Large artery-atherosclerosis, embolus/thrombosis

255 (7.5%)/254 (7.4%)

Cardioembolism, high-risk/medium-risk

74 (2.2%)/53 (1.5%)

Small-vessel occlusion, lacune

343 (10%)/247 (7.2%)

Other determined etiology (dissection, vasculitis, cerebral venous sinus thrombosis, others)

3 (0.1%)/2 (0.1%)

Undetermined etiology (two or more causes identified, negative evaluation, incomplete evaluation)

231 (6.8%)/220 (6.4%)