Chr. | Position hg38 | rsID | Gene(s) | Ref Allele | Alt Allele | HWE P-value | MAF | Model 0# P-value | Model 1 P-value | Model 2 P-value | Model 3 P-value | Model 4 P-value | Model 5 P-value |
---|
3 | 151678293 | rs6440776 | MIR5186-AADACL2 | C | T | 0.13 | 0.37 | 1.93E−07 | 3.71E−08 | 3.81E−08 | 5.59E−08 | 1.11E−07 | 2.02E−07 |
5 | 8496166 | rs57085808 | MIR4458HG−LINC02199 | G | C | 0.37 | 0.12 | 1.49E−06 | 2.70E−07 | 3.22E−07 | 3.13E−07 | 1.22E−06 | 6.40E−07 |
- *Only SNPs were included in the table if SNP has at least 5 SNPs in linkage disequilibrium (LD) within the genomic region and at least 3 of the models had P-value < 10−6
- #Model 0: stroke status ~ sex + age + PCs1 … 10 + SNP; model 1: stroke status ~ sex + age + PCs1 … 10 + SNP + hypertension; model 2: stroke status ~ sex + age + PCs1 … 10 + SNP + hypertension + diabetes; model 3: stroke status ~ sex + age + PCs1 … 10 + SNP + hypertension + diabetes + dyslipidemia; model 4: stroke status ~ sex + age + PCs1 … 10 + SNP + hypertension + diabetes + dyslipidemia + cardiac disease status; model 5: stroke status ~ sex + age + PCs1 … 10 + SNP + hypertension + diabetes + dyslipidemia + cardiac disease status + waist-hip ratio