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Fig. 7 | Genome Medicine

Fig. 7

From: Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features

Fig. 7

A Trinucleotide mutational signatures in each subsection of the phylogenetic tree for patient #15. B Pie charts showing increasing contribution of signature 3 in tree sub-sections HA, BC and IE compared to D and GF. C Immunohistochemical staining for PHH3 (positive in G2/M phase of cell cycle), plotted as the fraction of positive cells, shows a higher proportion in the tissue region corresponding to LPZMid

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Genome Medicine

ISSN: 1756-994X

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