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Fig. 8 | Genome Medicine

Fig. 8

From: Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features

Fig. 8

Pairs of H&E-stained sections (frozen: #02, #08, #15; FFPE: #10) corresponding to sequenced regions from each of four patients (4 × magnification). Histological differences within each pair are highlighted, and the corresponding branches of the phylogenetic trees are shown in the colours of the respective leaf/tip nodes. The total number of SNVs unique to either of the two histologically distinct samples are represented as ‘Unique SNVs’. GG, Gleason grade; IDC, intraductal carcinoma of the prostate

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