Fig. 3
From: An atlas of cell-type-specific interactome networks across 44 human tumor types
Topologically specific genes with cell-type-specific influence in pan-tumor myeloid cells. A The distribution of topologically specific scores (topS) is presented for each cell-type-specific network, focusing on canonical marker genes for a specific cell subset in pan-tumor myeloid cells. B Comparisons of genes prioritized by topS and tranS in various cell subsets of pan-tumor myeloid cells is depicted, with Jaccard indices calculated for the top-ranked 500 topS and tranS genes in each cell subset, and the number of shared genes displayed. C Scatterplots illustrating topologically specific genes with broad expression across different cell subsets in pan-tumor myeloid cells, with the best linear regression fit represented by the blue line and the top 5 genes with log2FC(PRtopS/PRtranS) are highlighted. The log2FC(PRtopS/PRtranS) represents log2 fold change between percentile ranks of topS and tranS