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Table 1 Anthropometric and clinical characteristics of the discovery cohort

From: Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians

Variable

Overall (n = 310)

T2D (n = 100)

Non-T2D (n = 210)

P-value*

Age (Years)

56.2 (17.7)

60.2 (11.9)

54.4(18.6)

0.0007Â¥

% Male

22.6

18

24.8

0.18

BMI (kg/m2)

30.5 (8.77)

32.6 (9.02)

30.2 (8.8)

0.15

PFM

38.9 (12.9)

40.5 (12.9)

38.1 (13.0)

0.1

Waist circumference (cm)

99.0 (16.0)

101.5 (16.00)

98.0 (16.50)

0.02Â¥

WHR

0.96 (0.07)

0.96 (0.10)

0.95 (0.08)

0.23

Glucose (mg/dl)

87.0 (21.0)

118.5 (62.00)

82.5 (13.00)

< 0.0001¥

Insulin (μU/mL)

7.8 (6.8)

9.2 (7.5)

7.2 (5.90)

0.008Â¥

HOMA-IR

1. 7 (1.9)

2.7 (3.00)

1.5 (1.3)

< 0.0001¥

Hba1c (%)

5.6 (1.1)

7.4 (2.6)

5.4 (0.50)

< 0.0001¥

Total cholesterol (mg/dl)

193.0 (73)

200.0 (75.5)

191.5 (71.5)

0.17

HDL-Cholesterol (mg/dl)

49.8 (20.4)

50.6 (23.9)

48.1 (19.8)

0.22

LDL-Cholesterol (mg/dl)

120.0 (64.0)

119.0 (60.5)

120.5 (66.0)

0.87

Triglycerides (mg/dl)

91.0 (47.0)

105.5 (65.5)

86.0 (45.5)

< 0.0001¥

  1. Data is displayed as median (interquartile range)
  2. Ratio compared by chi-square test
  3. BMI Body mass index, PFM Percentage fat mass, WHR Waist-to-hip ratio, HbA1c Hemoglobin A1c, TG Triglycerides, HDL High density lipoproteins, LDL Low density lipoproteins, T2D Individuals with T2D, Non-T2D Individuals without T2D
  4. *Medians were compared using the two-sample median test
  5. ¥denotes statistically different medians