Table 4 Metabolites in the T2D biomarker panels
| Â | Original (10-metabolite) panel | Restricted (7-metabolite) panel | ||
|---|---|---|---|---|
Discovery | Replication | Discovery | Replication | |
1,5-anhydroglucitol (1,5-AG) Methyl glucopyranoside (α + β) Fructosyl-lysine Gluconate Fructose 1-carboxyethylisoleucinea Mannonate Glucose Mannose Metformin | 1,5-anhydroglucitol (1,5-AG) Methyl glucopyranoside (α + β) Fructosyl-lysine Gluconate Fructose Mannonate Glucose Mannose Metformin | Methyl glucopyranoside (α + β) Fructosyl-lysine Gluconate Fructose 1-carboxyethylisoleucinea Mannonate Mannose | Methyl glucopyranoside (α + β) Fructosyl-lysine Gluconate Fructose Mannonate Mannose | |
AUC | 0.924 | 0.935 | 0.876 | 0.873 |
Predictive accuracy (%) | 89.3 | 88.8 | 85.4 | 79.5 |