Fig. 1From: NODAL variants are associated with a continuum of laterality defects from simple D-transposition of the great arteries to heterotaxyComprehensive pedigrees and their genotypes for families with NODAL variants. Standard pedigree structures are utilized—filled circles and squares denote clinically affected individuals, and probands are indicated by black arrows. A Pedigrees of probands harboring heterozygous NODAL variants. B Pedigrees of probands harboring biallelic NODAL variantsBack to article page