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Fig. 3 | Genome Medicine

Fig. 3

From: NODAL variants are associated with a continuum of laterality defects from simple D-transposition of the great arteries to heterotaxy

Fig. 3

Heart depictions illustrating anatomy, blood flow (yellow arrows) and oxygenation (color coded red for oxygenated, blue for unoxygenated, and purple for poorly oxygenated) for different heart defects compared to A the normal heart anatomy. These include B dextro-transposition of the great arteries (DTGA), C double outlet right ventricle with D-malposed great arteries, D tricuspid atresia with D-malposed great arteries, E congenitally corrected transposition of the great arteries (CCTGA) with left ventricular looping and L-transposition of the great arteries, F double inlet left ventricle (DILV) with L-looped ventricles. CCTGA and DILV are illustrated with dextrocardia, but may be levocardic or dextrocardic. G Heterotaxy, asplenia syndrome/right atrial isomerism type

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