Table 2 Number of participants with CF-causing variants across ancestries
Ancestries | Sample size in UKBB | CFTR variants | CF-causing | Varying clinical consequences (VCC) | High-impact variants |
|---|---|---|---|---|---|
AFR | 6278 | 417 | 22 | 12 | 16 |
AMR | 950 | 151 | 7 | 10 | 4 |
CSA | 8470 | 471 | 17 | 6 | 15 |
EAS | 2608 | 266 | 8 | 6 | 4 |
EUR | 397,073 | 3192 | 116 | 29 | 150 |
MID | 1498 | 222 | 8 | 12 | 7 |
MIX | 37,850 | 1333 | 85 | 29 | 70 |