Fig. 2

Smoke injury dynamics. a Plot showing the change of reversibility dynamics for the 749 response genes in the healthy volunteer (left) and clinic (right) donor groups (genes classified as unaffected by smoking in both donor groups were removed). Color bars represent the number of genes in each reversibility class (blue = rapidly reversible, yellow = slowly reversible, red = irreversible, green = cessation associated, grey = unaffected by smoking). b Normalized gene expression over smoking status for 4 exemplar response genes with different post-cessation dynamics in the clinic and healthy groups, with linetype and shape representing donor status (plain line = clinic group, dashed line = healthy volunteer) and colors representing the genes’ assigned reversibility classes (same color code as panel a). See also Fig. S1 for schematic examples