Skip to main content
Fig. 1 | Genome Medicine

Fig. 1

From: Single-cell transcriptomics reveal distinct immune-infiltrating phenotypes and macrophage–tumor interaction axes among different lineages of pituitary neuroendocrine tumors

Fig. 1

Single-cell analysis reveals the transcriptomic landscape in PitNETs. A Graphic overview of the study design and workflow. B Uniform Manifold Approximation and Projection (UMAP) map visualizes 69,539 cells, with color-coding representing individual samples. C UMAP overview color-coded by the three lineages observed. D UMAP overview color-coded by the identified cell types. E Violin plots depict marker gene expression levels across three types of tumor cells and immune cells. F Dot plot illustrating the specific marker genes associated with the 11 major cell types. G Heatmap displaying the chromosomal map of single-cell large-scale copy number variations (CNVs) inferred through scRNA-seq. Immune cells were used as a reference, and amplifications (red) or deletions (blue) were inferred by averaging expression over 100-gene stretches on each chromosome

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us