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Erratum to: A whole genome association study of mother-to-child transmission of HIV in Malawi

Genome Medicine volume 2, Article number: 76 (2010) Cite this article

The Original Article was published on 01 March 2010

Abstract

A correction to: Bonnie R Joubert, Ethan M Lange, Nora Franceschini, Victor Mwapasa, Kari E North, Steven R Meshnick andthe NIAID Center for HIV/AIDS Vaccine Immunology. A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Medicine 2010, 2:17.

We wish to report some corrections to our study [1], none of which alters the interpretation of the data or the conclusions drawn. After publication of this work we noted that the sample size required further clarification.

Results

A total of 246 infants (114 cases, 132 controls; 116 males, 121 females, 9 with imputed gender) passed laboratory quality control. Statistical quality control removed 15 individuals for low genotyping, resulting in a total of 231 individuals (103 cases, 128 controls; 114 males, 117 females). Of the 655,352 SNPs tested, 68,297 failed statistical quality control due to HWE P < 0.001 in the controls (N = 431), low genotyping rate (N = 21,589), or for MAF < 0.01 (N = 53,477), where some overlap of SNPs across exclusion criteria existed. Results were presented for 587,055 SNPs.

Additional data files

Additional data files 1 and 2 containing the corrected data are available online with this article.

References

  1. Joubert Bonnie R, Lange Ethan M, Franceschini Nora, Mwapasa Victor, North Kari E, Meshnick Steven R, the NIAID Center for HIV/AIDS Vaccine Immunology: A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Medicine. 2010, 2: 17-

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Authors and Affiliations

  1. Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27599, USA

    Bonnie R Joubert, Nora Franceschini, Kari E North & Steven R Meshnick

  2. Department of Genetics, School of Medicine, University of North Carolina, Chapel Hill, NC, 27599, USA

    Ethan M Lange

  3. Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27599, USA

    Ethan M Lange

  4. Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, 27599, USA

    Ethan M Lange & Kari E North

  5. College of Medicine, University of Malawi, Blantyre, Malawi

    Victor Mwapasa

Authors
  1. Bonnie R Joubert
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  2. Ethan M Lange
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  3. Nora Franceschini
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  4. Victor Mwapasa
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  5. Kari E North
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  6. Steven R Meshnick
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Consortia

the NIAID Center for HIV/AIDS Vaccine Immunology

Corresponding author

Correspondence to Bonnie R Joubert.

Additional information

The online version of the original article can be found at 10.1186/gm138

Electronic supplementary material

13073_2010_197_MOESM1_ESM.DOCX

Additional file 1: A Word document giving effect estimates for top SNPs of interest, by mode of transmission. The data provided represent the genome-wide association analysis by mode of HIV transmission. (DOCX 17 KB)

13073_2010_197_MOESM2_ESM.DOCX

Additional file 2: A Word document giving effect estimates for SNPs near or within genes associated with HIV/AIDS. The data provided represent the genome-wide association analysis for specific regions that have previously demonstrated association with HIV/AIDS, described in the Introduction section. (DOCX 73 KB)

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Joubert, B.R., Lange, E.M., Franceschini, N. et al. Erratum to: A whole genome association study of mother-to-child transmission of HIV in Malawi. Genome Med 2, 76 (2010). https://doi.org/10.1186/gm197

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  • DOI: https://doi.org/10.1186/gm197

Genome Medicine

ISSN: 1756-994X

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