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Table 1 Summary of variant positions found

From: A map of human microRNA variation uncovers unexpectedly high levels of variability

Origin Population Subjects SNVs SNVs in dbSNP SVNs in precursor SVNs in mature Number of heterozygous Number of homozygous miRNA with disease Diseases
European IBS 14 78 75 70 15 52 26 21 76
  AND 60 92 77 81 21 55 37 30 82
  CEU 85 132 119 116 29 87 45 42 102
  TSI 98 147 127 120 32 104 43 120 109
  GBR 89 131 114 110 28 80 51 43 107
  FIN 93 118 103 102 25 72 46 36 95
Asian CHS 100 114 92 93 28 65 49 30 88
  CHB 97 123 99 104 25 77 46 30 91
  JPT 89 120 108 103 32 72 42 38 96
American MXL 66 132 111 110 34 82 50 38 90
  PUR 55 152 141 117 35 107 45 41 85
  CLM 60 141 124 114 28 90 51 37 88
African LWK 97 229 187 179 59 158 71 70 104
  ASW 61 206 177 158 54 145 60 60 108
  YRI 88 207 175 169 53 130 77 169 133
  1. Origin, geographical origin of the population; Population, population code according to the 1000 Genomes Project (see Materials and methods); Subjects, number of sequenced subjects per population; SNVs, number of SNVs found in the population; SNVs in dbSNP, how many of these variants are already described in dbSNP; SVNs in precursor, how many of the SNVs map within the miRNA precursor structure (Figure 3, bottom); SVNs in mature, how many of the SNVs map within the miRNA mature structure (Figure 2, bottom); Number of heterozygous, the number of times that the SNV occurred heterozygously; Number of homozygous, the number of times that the alternative allele occurred homozygously; miRNA with disease, the number of miRNAs associated with at least one known disease, with at least one SNV, in the corresponding population; Diseases, the total number of diseases with which the miRNAs are associated.