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Table 2 Vaginal microbiota composition according to disease state

From: The vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasia

 

CST I (L. crispatus)

CST III (L. iners)

CST IV (Lactobacillus sp. deplete, high diversity)

Analysis 1

 Pre-treatment, n = 103

45/103 (44)

37/103 (36)

21/103 (20)

 Control, n = 39

22/39 (56)

16/39 (41)

1/39 (3)

p value

0.1920

0.6978

0.0081

Analysis 2

 Pre-treatment, n = 103

45/103 (44)

37/103 (36)

21/103 (20)

 Post-treatment, n = 103

40/103 (39)

44/103 (43)

19/103 (18)

p value

0.5715

0.3922

0.8604

Analysis 3

 Post-treatment, n = 103

40/103 (39)

44/103 (43)

19/103 (18)

 Control, n = 39

22/39 (56)

16/39 (41)

1/39 (3)

p value

0.0873

1.000

0.0142

Sub-group analysis 3A

 Post-treatment, normal cytology, n = 81

32/81 (40)

35/81 (43)

14/81 (17)

 Control, n = 39

22/39 (56)

16/39 (41)

1/39 (3)

p value

0.1166

0.8463

0.0354

Sub-group analysis 3B

 Post-treatment, normal cytology, HPV-negative, n = 70

27/70 (38)

30/70 (43)

13/70 (19)

 Control, HPV negative, n = 23

12/23 (52)

10/23 (44)

1/23 (4)

p value

0.3309

1.0000

0.1758

  1. p values represented are two-tailed Fisher’s exact (if < 5 observations in any group) and χ2 tests (where > 5 observations in every group)
  2. CST community state type, L. Lactobacillus, HPV human papillomavirus