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Table 2 Vaginal microbiota composition according to disease state

From: The vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasia

  CST I (L. crispatus) CST III (L. iners) CST IV (Lactobacillus sp. deplete, high diversity)
Analysis 1
 Pre-treatment, n = 103 45/103 (44) 37/103 (36) 21/103 (20)
 Control, n = 39 22/39 (56) 16/39 (41) 1/39 (3)
p value 0.1920 0.6978 0.0081
Analysis 2
 Pre-treatment, n = 103 45/103 (44) 37/103 (36) 21/103 (20)
 Post-treatment, n = 103 40/103 (39) 44/103 (43) 19/103 (18)
p value 0.5715 0.3922 0.8604
Analysis 3
 Post-treatment, n = 103 40/103 (39) 44/103 (43) 19/103 (18)
 Control, n = 39 22/39 (56) 16/39 (41) 1/39 (3)
p value 0.0873 1.000 0.0142
Sub-group analysis 3A
 Post-treatment, normal cytology, n = 81 32/81 (40) 35/81 (43) 14/81 (17)
 Control, n = 39 22/39 (56) 16/39 (41) 1/39 (3)
p value 0.1166 0.8463 0.0354
Sub-group analysis 3B
 Post-treatment, normal cytology, HPV-negative, n = 70 27/70 (38) 30/70 (43) 13/70 (19)
 Control, HPV negative, n = 23 12/23 (52) 10/23 (44) 1/23 (4)
p value 0.3309 1.0000 0.1758
  1. p values represented are two-tailed Fisher’s exact (if < 5 observations in any group) and χ2 tests (where > 5 observations in every group)
  2. CST community state type, L. Lactobacillus, HPV human papillomavirus