Fig. 4

Carbapenemase-carrying signatures are found in diverse species, lineages, and plasmid backgrounds. a Species phylogenies for all geographic signature-containing isolates from each species, showing sequence type (STs). b Within each ST, core SNV distances are shown (heatmap). c For each isolate, columns indicate plasmid content, and colored icons indicate signatures present on these plasmids. For the nested signatures 5.1-CP and 5.6-CP, a solid yellow circle indicates the presence of 5.1-CP only, whereas the yellow circle with a darker ring indicates the presence of both 5.1-CP and 5.6-CP. d Year of isolation is marked for each, colored by signature content as in c