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Tumor immune microenvironment and immunotherapy

Read new articles in our current special issue, including the guest editors' editorial and longitudinal monitoring of the neoantigen landscape in colorectal cancer. 

Precision of epigenetic clock estimates

Peter Visscher and colleagues present improved precision of the epigenetic clock and its association with mortality.

'Variant Interpretation for Cancer' tool

Max He, Kai Wang, and colleagues present their novel tool that standardizes and accelerates the interpretation of somatic variants in cancer.

Call for papers: Translating the microbiome

Submit to our special issue, guest edited by Ramnik Xavier. We aim to capture insights into all aspects of the human microbiome in health and disease.

A Decade of Genome Medicine

2019 is the 10th anniversary of Genome Medicine! This collection revisits some of our favorite articles. 

Reviews, Research Highlights and Commentaries

Read authoritative Reviews, Opinions and other content commissioned by the Genome Medicine Editors from leading researchers:

Reviews

Research Highlights

Commentaries (including Editorials, Comments, Opinions, Q&As and Meeting reports)

Articles

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Focus: Cancer

Read the latest papers on the cancer across BMC flagship journals.

Tissue-infiltrating lymphocytes signature predicts survival in patients with early/intermediate stage hepatocellular carcinoma​​​​​​
Meng-Xin Tian, Wei-Ren Liu, Han Wang, Yu-Fu Zhou, Lei Jin, Xi-Fei Jiang, Chen-Yang Tao, Zheng Tang, Pei-Yun Zhou, Yuan Fang, Wei-Feng Qu, Zhen-Bin Ding, Yuan-Fei Peng, Zhi Dai, Shuang-Jian Qiu, Jian Zhou, Wan Yee Lau, Jia Fan & Ying-Hong Shi
Published in BMC Medicine 05 June 2019

VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX

Florian Bonin, Karim Taouis, Paula Azorin, Ambre Petitalot, Zakia Tariq, Sebastien Nola, Nadège Bouteille, Sandrine Tury, Sophie Vacher, Ivan Bièche, Khadija Ait Rais, Gaelle Pierron, Laetitia Fuhrmann, Anne Vincent-Salomon, Etienne Formstecher, Jacques Camonis, Rosette Lidereau, François Lallemand & Keltouma Driouch 

Published in BMC Biology 02 October 2018

Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations​​​​​​​
Elen Kristine Höglander, Silje Nord, David C. Wedge, Ole Christian Lingjærde, Laxmi Silwal-Pandit, Hedda vdL Gythfeldt, Hans Kristian Moen Vollan, Thomas Fleischer, Marit Krohn, EllenSchlitchting, Elin Borgen, Øystein Garred, Marit M. Holmen, Erik Wist, Bjørn Naume, Peter Van Loo, Anne-Lise Børresen-Dale, Olav Engebraaten & Vessela Kristensen
Published in Genome Medicine 29 November 2019

VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer
Andrew N. Holding, Federico M. Giorgi, Amanda Donnelly, Amy E. Cullen, Sankari Nagarajan, Luke A. Selth & Florian Markowetz 
Published in Genome Biology 13 May 2019

Aims and scope

Genome Medicine publishes important advances of broad interest in the application of genetics, genomics and multi-omics to understand, diagnose and treat disease. The Journal aims to bridge the basic science and clinical research communities in areas that include, but are not limited to: cancer genomics, immuno-oncology, immunogenomics, infectious disease, microbiome, neurogenomics, systems medicine, clinical genomics, gene therapies, precision medicine, and clinical trials. The Journal content includes original research, method, software, database and guideline articles as well as reviews, opinions and commentaries. 

Article collections

Special issue
Tumor immune microenvironment and immunotherapy
Guest editors: Zlatko Trajanoski and Noel de Miranda

Special issue
From genome integrity to cancer
Guest editor: Serena Nik-Zainal

Special issue
Genomics of infection and immunity
Guest editors: Bali Pulendran and Mark Davis

Special issue
Disease Neurogenomics
Guest editors: Joseph Buxbaum and Catalina Betancur

See all article collections

Reviews, Research Highlights and Commentaries

Read authoritative Reviews, Opinions and other content commissioned by the Genome Medicine Editors from leading researchers:

Reviews

Research Highlights

Commentaries (including Editorials, Comments, Opinions, Q&As and Meeting reports)

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